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Skin is the outer layer of the body. In human being, it is the largest organ of the system that covers our body. Our skin has a function to protect our body from infection and extreme temperatures, maintain fluid balance, and synthesize vitamin D for our personal needs.
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Skin has three main layers, which are Epidermis, Dermis, and Hypodermis that have their respective tasks and need each other. The Epidermis layer is the outermost layer of the skin. This layer does not contain blood vessels, and is formed from Merkel cells, keratinocytes, with melanocytes and Langerhans cells. Under the Epidermis layer, there is Dermis layer. This layer contains hair follicles, sweat glands, sebaceous glands, apocrine glands, lymphatic vessels and blood vessels. This layer is connected to the Epidermis layer with the basement membrane. Structurally, this layer is divided into two regions, which are the region next to the epidermis called the Papillary region, and the thick inner region that is known as the Reticular region. Furthermore, there is Hypodermis layer which located below the Dermis layer. This layer is known as Subcutaneous tissue. Hypodermis serves to attach the skin to the underlying bone and muscle and supply them with blood vessels and nerves. The combination of these three main layers has an average thickness of 1 mm.
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